The Firm You Go to When the 
Stakes Are High

Invokana/SGLT2 Inhibitors Amputation, Genital Infection and Cancer Injuries

Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors is a class of medication used to manage Type 2 diabetes in adults. Along with diet and exercise, SGLT2 Inhibitors can lower blood sugar levels in Type 2 diabetics. The U.S. Food and Drug Administration (FDA) has issued warnings about serious complications that can occur with the use of several types of SGLT2 Inhibitors. These conditions include Fournier’s gangrene, leg and foot amputations, and kidney and bladder cancer. Thousands of people have filed lawsuits against the manufacturers of SGLT2 Inhibitor medications after developing serious and fatal side effects from these drugs.

SGLT2 Inhibitors Lawyers are Ready to Help

Contact our SGLT2 Inhibitors Lawyers to review whether you or a family member may be entitled to financial compensation. Levy Konigsberg LLP is currently accepting SGLT2 Inhibitor cases in all 50 states.

If you or a loved one has suffered one or more of these complications, you may be entitled to a cash award and compensation for medical expenses. For a free confidential consultation with SGLT2 Inhibitors Lawyers at our law firm, please call (800) 315-3806 or submit an email inquiry.

What Are Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors?

SGLT2 Inhibitors are a class of drugs that includes:

  • Invokana (active ingredient: canagliflozin);
  • Invokamet (active ingredients: canagliflozin and metformin);
  • Farxiga (active ingredient: dapagliflozin);
  • Xigduo XR (active ingredients: dapagliflozin and metformin extended-release);
  • Jardiance (active ingredient: empagliflozin);
  • Glyzambi (active ingredients: empagliflozin and linagliptin); and
  • Synjardy (active ingredients: empagliflozin and metformin).

SGLT2 Inhibitors are designed to treat Type 2 diabetes by blocking SGLT2, an agent that controls the reabsorption of glucose into the bloodstream. The medication causes glucose to be expelled into the urine, thereby lowering blood glucose levels. SGLT2 Inhibitors were considered a medical breakthrough for treating Type 2 diabetes when they were first approved by the FDA in 2013.

What is Happening with Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors?

The FDA announced new warnings for several drugs in the SGLT2 Inhibitor class as a result of serious complications reported by users. Despite the addition of FDA warnings, thousands of lawsuits have been filed by consumers as a result of the manufacturer’s failure to inform the public about these dangerous side effects.

In August 2018, the FDA reported cases of a serious infection of the genitals and area surrounding the genitals, known as necrotizing fasciitis of the perineum or Fournier’s gangrene, in users of certain SGLT2 Inhibitors including Invokana, Farxiga and Jardiance. The FDA required new warning labels to advise patients of the risk of developing this condition. Fournier’s gangrene is a bacterial infection of the tissues around the perineum area. Diabetic patients are more likely to develop this condition. Between March 2013 and May 2018, 12 cases of Fournier’s gangrene were reported in patients taking SGLT2 Inhibitors. The 12 reported cases required hospitalization and surgery, and one resulted in death.

In a separate communication, the FDA warned that SGLT2 Inhibitors with the active ingredient canagliflozin increased the risk of leg and foot amputations. As a result of adverse events associated with the use of SGLT2 Inhibitors containing canagliflozin, the FDA revamped the labeling of the medication. The FDA included a Black Box Warning in 2017 after clinical trials found that leg and foot amputations were twice as likely in patients taking canagliflozin than those taking a placebo. Amputations typically involved the toe and middle of the foot, while a smaller number affected the leg below or above the knee, or both legs.

A third complication associated with SGLT2 Inhibitors is kidney and bladder cancer. In 2011, an increase in bladder cancer in users of SGLT2 Inhibitors (in particular dapagliflozin) was reported in findings submitted by the FDA. Excessive reports of male bladder cancer in preclinical trials delayed approval of the drug in 2012. The link between SGLT2 Inhibitors and kidney and bladder cancer continues to be investigated.

https://www.fda.gov/Drugs/DrugSafety/ucm617360.htm

https://www.fda.gov/Drugs/DrugSafety/ucm557507.htm

https://sciencetrends.com/cancer-risk-found-associated-novel-diabetes-medications-sglt2-inhibitors/

Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors Side Effects and Complications

Serious side effects of SGLT2 Inhibitors include:

  • Necrotizing fasciitis of the perineum or Fournier’s gangrene (genital infection);
  • Amputation of the leg and foot;
  • Kidney failure;
  • Ketoacidosis; and
  • Increased risk of bladder and kidney cancer.

Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors Lawyers are Ready to Help

Contact our SGLT2 Inhibitors Lawyers to review whether you or a family member may be entitled to financial compensation. Levy Konigsberg LLP is currently accepting SGLT2 Inhibitors cases in all 50 states.

If you or a loved one has suffered one or more of these complications, you may be entitled to a cash award and compensation for medical expenses. For a free confidential consultation with SGLT2 Inhibitors Lawyers at our law firm, please call (800) 315-3806 or submit an email inquiry.

A TEAM COMMITTED TO DOING WHAT IS RIGHT

Find out whether you have a case by speaking to one of our experienced mesothelioma lawyers via our 24/7 toll-free hotline or by submitting an email inquiry. Our attorneys will be quick to respond to you and happy to answer all of your questions.

Know the Difference

Committed to Doing What's Right
  • Over $3 Billion Won

    We have represented numerous individuals and groups of workers, winning for them multi-million-dollar settlements and verdicts.

  • There's No Case Too Big

    Our team has achieved groundbreaking victories in highly complex cases and has gone up against some of the toughest defendants in the country.

  • Trial Attorneys

    Our attorneys excel in the courtroom and are not afraid to bring a case in front of a jury if a fair settlement for the client has not been reached.

  • A Thought Leader in the Industry

    Our firm's knowledge and experience are in high demand, and many news outlets have asked us to share our legal expertise.

  • Access to World Class Resources

    Our experienced attorneys use cutting-edge technology and highly regarded experts to help us achieve the best possible result for our clients.

  • Changing the World for Good

    We not only want to achieve the best possible results for our clients, but we also strive to prevent future harm by changing public health policies.

Thousands of Clients Helped

Hear What They Have to Say
  • They truly made a difference in our lives!

    “Levy Konigsberg went above and beyond in representing my father in his mesothelioma case against multiple parties. From providing a risk free introduction (even flying out at their expense to speak to my father in person) to fighting diligently for us.”

    - Jonathan McNulty
  • Outstanding law firm!

    “Jerry and Bob are not only experts in their field, but genuinely care about their clients. They explain the entire process in a step like manner and are keenly aware that the health and medical treatment of the defendant should not be compromised.”

    - R.M.
  • No need to look any further.

    “The attorneys were attentive to my fathers needs during all proceedings while at the same time aggressive with the defendants making sure my father got everything he deserved.”

    - Todd Allen
  • They were the clear choice!

    “Jerry Block was compassionate and assembled a team of attorneys that knew exactly what to do. Although no amount of money can replace my father, we are grateful to them for giving him the gift of knowing that his family would be taken care of.”

    - Bruce Totterdale
  • Forever grateful!

    “They were not only knowledgeable but also compassionate. It was comforting to know they were diligently working on his case so we could focus on his medical care. Levy Konigsberg became part of our journey and we are forever grateful.”

    - Diane Hoefer
  • The best and brightest!

    “They never failed to keep us informed of all important developments in the case, and they always gave a realistic idea of when the matter would be resolved. I always felt that my dad was excellently represented, and that his case was in the best hands.”

    - Paulette
  • Simply incredible!

    “Corey Stern was simply incredible! Not only did he keep me well informed as to what was transpiring with my case, but was direct and honest all the way through. His hard work and compassion resulted in an amazing settlement.”

    - IBS LMM
  • Knowledgeable guidance and representation.

    “Your firm explained all of the steps involved in filing my case, took the time to update me as it progressed, prepared me for my meeting with NYS officials… Without your knowledgeable guidance and representation, I may not have been successful.”

    - Steven Simon
  • They are good people who want to help you.

    “I am now in a more comfortable financial situation. I can now go out and buy myself the things I need, without worrying how I am going to do that. Because I am well aware that I am not capable of getting or keeping a job.”

    - Edwin Jimenez
  • They won us a lot of money.

    “Levy Konigsberg, in my opinion, is a great law firm. They took very well care of us and I believe that they cared very much about our case. They were great attorneys.”

    - Karen
LEVY KONIGSBERG IN THE NATIONAL MEDIA

CHOOSE LEVY KONIGSBERG

Start with a FREE Consultation
  • Please enter your first name.
  • Please enter your last name.
  • Please enter your phone number.
    This isn't a valid phone number.
  • Please enter your email address.
    This isn't a valid email address.
  • Please make a selection.
  • Please enter a message.